Medicament delivery device adapted for long term storage

ABSTRACT

A medicament delivery device is presented having a housing, a medicament container holder arranged to accommodate a medicament container provided with a medicament delivery member, a power unit arranged to act on the medicament container for expelling a dose of medicament when activated, an activation mechanism operably connected to the power unit. The activation mechanism is capable of activating said power unit and includes a medicament delivery member guard movable in a longitudinal direction in relation to the housing. The activation mechanism also has a force element arranged to bias said medicament delivery member guard to a proximal extended position wherein said medicament delivery member is covered and has a locking mechanism operably arranged to lock the medicament delivery member guard in the extended position, where the locking mechanism has a number of locking elements connected to the medicament delivery member guard and flexible in a generally radial direction.

CROSS REFERENCE TO RELATED APPLICATIONS

The present application is a continuation of U.S. patent applicationSer. No. 16/348,847 filed May 9, 2019, which is a U.S. National PhaseApplication pursuant to 35 U.S.C. § 371 of International Application No.PCT/EP2017/077744 filed Oct. 30, 2017, which claims priority to EuropeanPatent Application No. 16199478.5 filed Nov. 18, 2016. The entiredisclosure contents of these applications are herewith incorporated byreference into the present application.

TECHNICAL AREA

The present disclosure relates to a medicament delivery devicecomprising a large number of automatic features.

BACKGROUND

Medicament delivery devices with a number of features, in particularautomated features, such as e.g. penetration, injection, withdrawal andcovering of medicament delivery members have gained increasingpopularity during the last 10-15 years.

Many of these highly automated medicament delivery devices, so calledauto-injectors, are used for medicament that is to be taken duringemergency situations and then often by unexperienced users. One verycommon medicament that is used in connection with auto-injectors isadrenalin that is administered for emergency treatment of anaphylaxis.

There are large numbers of these types of adrenaline medicament deliverydevices placed in the society such as schools, museums, shopping mallsetc. as emergency devices should a person suffer from an anaphylacticshock. Helping personnel such as teachers, guards, salespersons, etc.could then use an auto-injector with adrenaline to treat the person inchock.

These and many other medicament delivery devices with different types ofdrugs are often stored for long periods before being used. The majorityof this type of medicament delivery device is made of components andelements of plastic material that may change properties when aging.Further, many functions of these devices comprise tongues, fingers,arms, levers and other elements that are arranged to flex in differentdirections for releasing or locking functional components.

For example the medicament delivery device disclosed in document WO2013/032389 comprises a number of levers flexible in generally radialdirections for holding and releasing a medicament container holder forperforming a penetration, holding and releasing a plunger rod forperforming an injection and for blocking the movement of a medicamentdelivery member guard after removal of the medicament delivery devicefrom the medicament delivery site. Many of these levers, and inparticular the levers that block the medicament delivery member guardare in a flexed, tensioned condition in their initial state and flex toa non-tensioned blocking condition when the medicament delivery memberguard is to be blocked.

However, due to the effects of aging of plastic material and thetensioned condition, the levers may lose their flexing properties to alarge extent, which may jeopardize the blocking capabilities of thelevers, and thus may risk injuries if it is possible to move themedicament delivery member guard so that the medicament delivery memberis exposed.

SUMMARY

The aim of the disclosure is to remedy the drawbacks of the state of theart medicament delivery devices and to provide a solution that willensure full functionality even after longer storage periods.

The aim of the present disclosure is solved by a medicament deliverydevice comprising the features of the independent patent claims.Preferable embodiments of the disclosure form the subject of thedependent patent claims.

According to a main aspect of the disclosure, it comprises a medicamentdelivery device that may comprise a housing and a medicament containerholder arranged to accommodate a medicament container. Further themedicament delivery device may comprise a power unit arranged to act onsaid medicament container for expelling a dose of medicament whenactivated as well as an activation mechanism operably connected to thepower unit, capable of activating the power unit.

Preferably the activation unit comprises a medicament delivery memberguard movable in a longitudinal direction in relation to said housingsuch that when a proximal end of the medicament delivery device ispressed against a dose delivery site, wherein the activation unit maycomprise a force element arranged to bias the medicament delivery memberguard to a proximal extended position wherein the medicament deliverymember is covered.

The medicament delivery device may further comprise a locking mechanismoperably arranged to lock the medicament delivery member guard in theextended position, wherein the locking mechanism may comprise a numberof locking elements flexible in a generally radial direction. Thelocking mechanism may further comprise ledge surfaces to which thelocking elements abut when the medicament delivery member guard is inthe extended position, preventing any further movement of the medicamentdelivery member guard in the distal direction. This will effectivelyprevent any accidents of exposed medicament delivery members thatotherwise may cause injuries like needle sticks.

According to a favourable solution, the medicament delivery device maybe arranged with spaces connected to the housing in which the lockingelements are positioned in a non-tensioned state in a delivery mode ofthe medicament delivery device. With this solution, the locking elementswill not be in a tensioned state for longer periods of time whendelivered and stored for future use. The material of the lockingelements will thus not be affected and altered due to tensions in thematerial, thus ensuring proper functioning and flexing action of thelocking elements when the medicament delivery device is used, even afterlonger times of storage.

The spaces may be recesses or cut-outs on the inner surface of thehousing or on adjacent parts. According to one aspect of the disclosure,the spaces may be arranged on at least one separate component attachedinside the housing of the medicament delivery device. With this solutionit is easier to create the spaces or recesses than in the housingitself, because the latter is difficult from a manufacturingperspective. The separate component may be permanently or releasablyattached to the housing.

Further, the separate component may comprise an elongated plate-shapedmember, and the housing may be arranged with support elements preventingmovement of the component when assembled. In that regard, the supportelements may comprise a transversal stop element arranged to abut aproximal end of the at least one component. The transversal stop elementmay be comprised in the housing. This solution enables the plate-shapedmember to be pushed or slid into the housing from a distal direction viathe support elements until it is positioned by the abutment to thetransversal stop element. Preferably the support elements may compriselongitudinally extending ledges arranged to support the at least onecomponent in all transversal directions.

In order to fixate the plate-shaped member, the support elements maycomprise a transversal stop element arranged to abut a distal end of theat least one component and according to one aspect, the support elementmay be comprised in a component attachable to the housing, such as anend cap that is attached to the distal end of the housing.

Further, the at least one element may also comprise the ledge surfacesof the locking mechanism. This has the advantage that the manufacturingis facilitated in that the manufacturing and the molds of the housingare less complex.

These and other aspects of, and advantages with, the present disclosurewill become apparent from the following detailed description of thedisclosure and from the accompanying drawings.

BRIEF DESCRIPTION OF DRAWINGS

In the following detailed description of the disclosure, reference willbe made to the accompanying drawings, of which

FIG. 1 is an exploded view of one embodiment of a medicament deliverydevice comprising the present disclosure,

FIG. 2 is a detailed views of components comprised in the medicamentdelivery,

FIG. 3 is a detailed views of components comprised in the medicamentdelivery device of FIG. 1,

FIG. 4A is a cross-sectional view of the medicament delivery device ofFIG. 1,

FIG. 4B is a cross-sectional views of the medicament delivery device ofFIG. 1,

FIG. 5A is a cross-sectional view of a power unit comprised in themedicament delivery device of FIG. 1,

FIG. 5B is a cross-sectional view of a power unit comprised in themedicament delivery device of FIG. 1,

FIG. 6 is a detailed view of components comprised in the medicamentdelivery device of FIG. 1,

FIG. 7A is a detailed view of components comprised in the medicamentdelivery device of FIG. 1,

FIG. 7B is a detailed view of components comprised in the medicamentdelivery device of FIG. 1,

FIG. 8 is a detailed view of components comprised in the medicamentdelivery device of FIG. 1,

FIG. 9 is a detailed view of components comprised in the medicamentdelivery device of FIG. 1,

FIG. 10 is a detailed view of components comprised in the medicamentdelivery device of FIG. 1,

FIG. 11A is a detailed view of components comprised in the medicamentdelivery device of FIG. 1,

FIG. 11B is a detailed view of components comprised in the medicamentdelivery device of FIG. 1,

FIG. 12 is a detailed view of components comprised in the medicamentdelivery device of FIG. 1,

FIG. 13 is a detailed view of components comprised in the medicamentdelivery device of FIG. 1,

FIG. 14A is a view of a different functional stage of the medicamentdelivery device of FIG. 1,

FIG. 14B is a view of a different functional stage of the medicamentdelivery device of FIG. 1,

FIG. 15 is a view of a different functional stage of the medicamentdelivery device of FIG. 1,

FIG. 16 is a view of a different functional stage of the medicamentdelivery device of FIG. 1,

FIG. 17 is a view of a different functional stage of the medicamentdelivery device of FIG. 1, and

FIG. 18 is a view of a different functional stage of the medicamentdelivery device of FIG. 1.

DETAILED DESCRIPTION

The present disclosure relates to a medicament delivery device providedwith an elongated housing 10 extending along a longitudinal axis L andhaving a proximal end 12 and distal end 14. The proximal end of thehousing 10 is arranged with a tubular section 16, onto which aprotective cap 164 is arranged to be releasably attached. A transversaltransitional wall 20 is arranged between the tubular section 16 and therest of the housing 10. The distal end 14 of the housing is arrangedwith a central opening 22, to which an end cap 138 may be attached. Thedistal area of the housing is arranged with arms 29 that are flexible ina generally radial direction, which arms are arranged with inwardlydirected ledges for attaching the end cap 138 as will be describedbelow. Further the proximal end 12 of the housing 10 is arranged with anopening 26. Moreover, an opening or window 28 is arranged on the side ofthe housing.

A medicament delivery member guard, in the embodiment shown comprising afront medicament delivery member guard 30 and a rear medicament deliverymember guard 48 that are comprised in an activation mechanism as will bedescribed, FIGS. 1 and 2, is further arranged slidable in the housing10. The front medicament delivery member guard 30 is arranged with aproximal generally tubular part 32 that may protrude through the opening26 at the proximal end of the housing. The tubular part 32 is arrangedwith proximally directed tongues 34 formed in the tubular part 32 byU-shaped cut-outs. The tongues 34 are flexible in the generally radialdirection and are arranged with outwardly extending protrusions 36. Atthe distal end of the proximal part 32, two generally flat arms 38 areextending in the distal direction. At the junction between the proximalpart 32 and the arms 38, tongues 40 are attached, which extend in thedistal direction at some outwards inclination in relation to alongitudinal axis. The tongues 40 are designed and attached to theproximal part 32 such that proximal end surfaces 42 of the tongues 40are created. At a distal end of the arms 38, cut-outs 44 are arranged.Further, protrusions 46 are positioned on the inner surface of the arms38 proximal of and adjacent the cut-outs 44. Distally directed endsurfaces of the protrusions 46 are arranged to abut proximal endsurfaces of the rear medicament delivery member guard 48. The rearmedicament delivery member guard 48 is arranged as a tubular body 50. Ata proximal area of the tubular body 50, two radially extending ledges 52are arranged around the circumference. Between the two ledges 52 arerectangular cut-outs 54 that extend in the longitudinal direction. Atthe distal end of the tubular body 50, two arms 56 are extending in thedistal direction. The arms 56 are provided with rectangular cut-outs 58.

Further, inside and coaxial with the medicament delivery member guard 30is a medicament container holder 60, FIGS. 1 and 3, having a generalC-shape as seen in a cross-sectional view. The medicament containerholder 60 is arranged to contain a medicament container 62 that in theembodiment shown is a generally elongated syringe with a fixed injectionneedle 64 at its proximal end and having a movable stopper 65 enclosingthe distal end of the medicament container 62, FIG. 4. The injectionneedle 64 is preferably protected by a suitable medicament deliverymember shield 66, FIG. 4a . In the embodiment shown the medicamentdelivery member shield 66 is a so called flexible needle shield or FNS.It is however to be understood that other types of medicament deliverymember shields are feasible within the disclosure.

The distal end of the medicament container 62 is arranged with agenerally radially extending flange 68, and the medicament containerholder 60 is provided with a recess 70 in which the flange 68 fits, FIG.3. In order to secure the medicament container 62 in the medicamentcontainer holder 60 a generally C-shaped clip 72 is arranged which isdesigned to fit into the recess 70 and to engage with the walls of therecess 70 in order to securely hold the medicament container 62 insidethe medicament container holder 60. At the distal end of the medicamentcontainer holder 60, recesses 74 are arranged. These recesses 74 aredesigned to interact with proximally directed tongues 76 havingoutwardly directed ledges 78, which ledges 78 fit into the recesses 74.The proximally directed tongues 76 are attached to a generally tubularplunger holder 80, which plunger holder 80 is comprised in a power unit81 of the medicament delivery device, shown in FIG. 5. Adjacent theattachment points of the tongues 76, generally radially extending ledges82 are arranged. Further, cut-outs 84 are arranged on opposite sides ofthe body, having generally rectangular shapes. At the distal end of theplunger holder, two recesses 86 are arranged on opposite sides thereof.

The plunger holder 80 is further arranged with two distally directedarms 88 on opposite sides that are flexible in the generally radialdirection. The free ends of the arms 88 are arranged with inwardlydirected ledges 90, FIG. 5, and outwardly directed surfaces of the arms88 are arranged with radially directed protrusions 92. The inwardlydirected ledges 90 are designed to interact with circumferentialrecesses 94 on an outer surface of an elongated plunger rod 96, FIG. 6,which plunger rod 96 is arranged slidable in a longitudinal directioninside the plunger holder 80. The plunger rod 96 is further arrangedwith a circumferential, proximally directed, ledge 97 positioned at apredetermined distance from the proximal end of the plunger rod. A drivespring 98, FIGS. 1 and 5, that in the embodiments shown is a compressionspring is comprised in the power unit. The drive spring 98 is arrangedbetween a proximal end wall 100 of the plunger rod 96 and a distal endwall 102 of the plunger holder 80, FIG. 5a . An elongated spring guiderod 104, FIG. 4a , is arranged inside the drive spring 98 for preventingbuckling of the drive spring 98. Adjacent the free ends of the arms 88two distally directed support ledges 105, FIG. 3, are arranged onopposite sides, the function of which will be described below.

Coaxial with, and positioned radially outside the plunger holder, is anactuator 106, FIGS. 7 to 9, having a generally tubular first body 108.At a distal end of the first body two distally directed arms 110 arearranged, being flexible in the generally radial direction. The freeends of the arms 110 are arranged with inwardly directed ledges 112. Theledges 112 of the arms are arranged to fit into the recesses 86 of theplunger holder 80 for releasably holding the plunger holder 80 as willbe described below. Outside the tubular first body 108 and coaxialtherewith is a tubular second body 114, where the bodies are attached toeach other by longitudinally extending ribs 116. The second body 114 isarranged with two proximally directed tongues 118 that are flexible inthe generally radial direction. The free ends of the tongues 118 arearranged with inwardly directed ledges 120. The second body 114 isarranged with longitudinally extending slits 122 which terminate at theproximal end surface of the second body 114. Further, end sections 124are arranged between the first and the second bodies, which end sections124 are arranged with two generally rectangular first passages 126 and acentrally positioned generally rectangular second passage 128.

The actuator is held stationary by an actuator lock 130 in the form of agenerally U-shaped element. Proximally directed arms 132 of the actuatorlock 130 are arranged with generally rectangular cut-outs 134 extendingalong the arms 132. Each cut-out 134 is provided with distally directedtongues 136 that have a certain outwardly inclination. The proximallydirected arms 132 are designed to fit in the rectangular second passage128 and the annular space between the first 108 and the second 114bodies and extend such that the distal ends of the tongues 136 aredesigned to move out into the slits 122 of the second body and beresting with their end surfaces against proximally directed end surfacesof the slits 122, thereby locking them relative each other as seen inFIG. 7B.

An end cap 138 is further provided for the medicament delivery device,FIG. 8. It comprises a generally dome-shaped body 140 arranged to coverthe distal end of the housing. A number of support beams 142 extend inthe proximal direction, which support beams 142 are to rest against thedistally directed surface of the end sections 124 of the actuator 106.Further two attachment arms 144 are extending from the body 140 in theproximal direction. The attachment arms 144 have a generally rectangularcross-sectional shape and are intended to fit into the generallyrectangular first passages 126 of the end sections 124 of the actuator106. At the proximal area of the attachment arms are generallyrectangular cut-outs 146, which are intended to engage with the inwardlydirected ledges 120 of the tongues 118 of the second body 114 of theactuator 106 such that they are locked to each other when the attachmentarms 144 are pushed into the first passages 126. With this solution theactuator 106, the actuator lock 130 and the end cap 138 are thus lockedto each other when assembled. The assembly is in turn attached to thedistal end of the housing in that the inwardly directed ledges of thetongues 29 of the housing 10 fit into passages created around the armsof the second body as seen in FIG. 10.

A number of spring force elements are arranged in the power unit 81shown in FIGS. 5A-5B. A medicament delivery member guard spring 148 inthe form of a compression spring is arranged between distally directedsurfaces of the ledges 52 of the rear needle cover and proximallydirected end surfaces of the longitudinal ribs 116 between the first andthe second tubular bodies of the actuator 106. A penetration spring 150also in the form of a compression spring is arranged between thedistally directed support ledges 105 of the plunger holder 80 andproximally directed surfaces of the end sections 124 of the actuator106.

Further needle cover lock elements 152, FIGS. 2 and 11, are providedinside the housing of the medicament delivery device. The needle coverlock elements 152 comprise generally elongate plate-shaped members 154that extend from a proximal end of the second body 114 of the actuator106 to outside the needle cover as seen in FIG. 11A. The distal end ofthe members 154 are provided with cut-outs on each side such that acentral part 156 fits into the slit 122 of the second body 114 wheredistally directed end surfaces of the cut-outs are resting on theproximal end surface of the second body 114 on each side of the slit122, FIG. 11A. At the proximal area of the members 154 generallyrectangular cut-outs 158 are provided, the function of which will beexplained. On the inner surface of the members 154 at a proximal areathereof, FIGS. 2 and 12, transversal ledges 160 are arranged, designedto interact with the tongues 40 of the medicament delivery member guard30 as will be described. The needle cover lock element 152 is supportedin the proximal area by longitudinally extending guide ledges 162 on theinner surface of the housing 10. As seen in FIG. 12, the guide ledges162 are arranged such that the needle cover lock element 152 is guidedin all directions but the longitudinal.

Further, the medicament delivery device is arranged with a front cap164, FIGS. 1 and 13, arranged with a distally directed passage 166. Theshape of the passage 166 is to fit onto the proximal section 16 of thehousing with a friction fit to releasably hold the front cap 164 ontothe housing 10. The front cap 164 is further arranged with a distallydirected generally tubular body 168 having dimensions so as to fit intothe proximal end of the medicament delivery member guard 30. Inside thetubular body a medicament delivery member shield remover is arranged. Itcomprises a plate-shaped body 170 arranged with three distally directedarms 172. The ends of the arms 172 are arranged with inwardly directedledges 174, which ledges 174 are arranged to engage the outer surface ofa medicament delivery member shield 66. The outer surfaces of the arms172 are arranged with proximally directed, outwardly inclined, tongues176, which tongues 176 are designed to fit into longitudinal slits 178in the tubular body 168 such that the end surfaces of the tongues restagainst a distally directed surface of an end wall 180 of the front cap164.

The medicament delivery device is intended to function as follows. Whenthe medicament delivery device is assembled, a medicament container 62,with a medicament delivery member shield 66 attached to the injectionneedle 64, is preferably inserted into the medicament container holder60 and a C-clip 72 is attached so that the medicament container 62 issecurely attached to the medicament container holder 60. A drive spring98 is inserted into the plunger holder 80 and is tensioned by theplunger rod 96 being pushed in the distal direction into the plungerholder 80 until the ledges 90 of the arms 88 fit into the recesses 94 ofthe plunger rod 96. The first body 108 of the actuator 106 is thenpushed onto the plunger holder 80 in the proximal direction until theledges 112 of the arms 110 of the first body 108 fit into the recesses86 of the plunger holder 80, whereby the arms 110 are prevented fromflexing in the radial direction. The rear medicament delivery memberguard 48 is then pushed onto the first body 108 of the actuator 106 suchthat the arms 88 of the first body 108 are prevented from flexing in theradial direction. Thus, a power pack 81 is formed.

The needle cover locks 152 are pushed from the distal end into thehousing 10 of the medicament delivery device. In this regard, they areguided and supported in all transversal directions by the guide ledges162 as seen in FIG. 12. The medicament delivery member guard 30 is thenentered into the housing from the distal end, whereby the tongues 40will slide on the inner surface of the needle cover lock elements 152until they enter the cut-outs 158, where they will flex outwardly in theradial direction and be positioned in a non-tensioned state or conditionin a delivery mode, FIG. 11B. The medicament container holder 60 is nowattached to the plunger holder 80 and the whole assembly is insertedinto the housing from the distal end, which causes the needle cover lockelements 152 to be locked in the longitudinal direction by the centralpart 156 at the distal end of the needle cover locks fitting into theslits 122 of the actuator, FIG. 11A. Then the distal end of themedicament delivery device is closed by the actuator lock 130 and theend cap 138. Further, a front cap 164 is attached to the proximal end ofthe medicament delivery device.

When the medicament delivery device is to be used, the front cap 164 isremoved by pulling it in the proximal direction. The ledges 174 of themedicament delivery member shield grabber engage the material of themedicament delivery member shield 66 so that the medicament deliverymember shield 66 is also pulled off when the front cap 164 is removed.The device is now ready to deliver a dose of medicament. The proximalend of the medicament delivery device is then pressed against a dosedelivery site, i.e. the proximal end of the front medicament deliverymember guard. This causes the front medicament delivery member guard 30to move distally in relation to the housing and because the frontmedicament delivery member guard 30 is connected to the rear medicamentdelivery member guard 48, the latter will also move in the distaldirection in relation to the housing. Further, the tongues 40 movenon-tensioned in the recesses 158 of the members 154 of the needle coverlocks 152, FIG. 14A. When the medicament delivery member guard has moveda certain distance, the rectangular cut-outs 58 of the rear medicamentdelivery member guard 48 will be positioned radially outside the arms110 of the first body 108 of the actuator 106, which arms 110 are thenfree to flex radially outwards, thereby releasing the plunger holder 80.The plunger holder 80 is now moved in the proximal direction by theforce of the penetration spring 150, whereby the medicament containerholder 60 with its medicament container 62 is also moved in the proximaldirection, causing a penetration by the injection needle 64 into thedose delivery site, FIG. 14B.

As the plunger holder 80 is moving in the proximal direction during thepenetration sequence, it will also move in relation to the first body108 of the actuator 106. At the end of the penetration movement, theprotrusions 92 of the arms 88 of the plunger holder 80 holding theplunger rod 96 will pass out of contact with the inner surface of thefirst body 108, FIG. 15, wherein the arms 88 are free to flex radiallyoutwards, releasing the plunger rod 96. Because of the drive spring 98,the plunger rod 96 is now urged in the proximal direction, whereby thestopper 65 of the medicament container 62 is also moved in the proximaldirection, causing a dose of medicament to be delivered through theinjection needle 64. The dose delivery sequence is terminated when theproximal circumferential ledge 97 of the plunger rod 96 comes in contactwith a distal end surface of the medicament container holder 60, FIG.16.

The medicament delivery device can now be removed from the dose deliverysite. This enables the medicament delivery member guard 30, to be movedin the proximal direction relative the housing by the medicamentdelivery member guard spring 148 such that the injection needle 64 iscovered by the medicament delivery member guard 30, FIG. 17. Themovement of the medicament delivery member guard 30 is stopped when theproximally directed end surfaces 42 of the inclined tongues 40 of themedicament delivery member guard 30 come in contact with thetransitional wall 20 of the housing, FIG. 18. The movement of themedicament delivery member guard 30 will also cause the inclined tongues40 of the medicament delivery member guard 30 to move past the ledges160 of the needle cover lock elements 152, which will prevent anymovement of the medicament delivery member guard 30 in the distaldirection in relation to the housing, thereby preventing any exposure ofthe injection needle 64. The medicament delivery device can now bediscarded.

It is to be understood that the disclosure described above and shown inthe drawings is to be regarded only as a non-limiting example and thatit may be modified in many ways within the scope of the patent claims.

We claim:
 1. A medicament delivery device comprising: a housing; a powerunit; and a medicament delivery member guard operably connected to thepower unit, wherein the medicament delivery member guard is movable in alongitudinal direction in relation to the housing, wherein themedicament delivery member guard includes a tubular part including aproximal end and a distal end, wherein the proximal end of the tubularpart is arranged with proximally directed tongues formed in the tubularpart by U-shaped cut-outs, wherein the proximally directed tongues areflexible in a radial direction and are arranged with outwardly extendingprotrusions, and wherein a distal end of the tubular part includes twoarms are extending in a distal direction.
 2. The medicament deliverydevice of claim 1, wherein a distal end of each of the two arms of themedicament delivery member guard include a cut-out.
 3. The medicamentdelivery device of claim 2, wherein an inner surface of each of the twoarms of the medicament delivery member guard include protrusionspositioned the cut-out.
 4. The medicament delivery device of claim 1,further comprising: a second medicament delivery member guard that ismovable in a longitudinal direction in relation to the housingindependent from the medicament delivery member guard.
 5. The medicamentdelivery device of claim 1, further comprising: a locking elementpositioned on the medicament delivery member guard and flexible in theradial direction, wherein the locking element is configured to lock themedicament delivery member guard in an extended position after adelivery of a dose of medicament, wherein the locking element ispositioned in a non-tensioned state prior to the delivery of the dose ofmedicament.
 6. The medicament delivery device of claim 5, wherein thelocking element is positioned in the non-tensioned state during deliveryof the dose of medicament such that the locking element movesnon-tensioned during the delivery of the dose of medicament.
 7. Themedicament delivery device of claim 5, wherein the housing includes aledge surface axially fixed relative to the housing, wherein the lockingelement flexes radially outward and abuts the ledge surface when themedicament delivery member guard is moved to the extended position suchthat further movement of the medicament delivery member guard in thedistal direction is prevented.
 8. The medicament delivery device ofclaim 7, wherein recesses or cutouts are positioned and axially fixedrelative to the housing.
 9. The medicament delivery device of claim 8,wherein the recesses or cutouts are arranged on a separate componentattached inside the housing of the medicament delivery device.
 10. Themedicament delivery device of claim 9, wherein the separate component isreleasbly attached to the housing of the medicament delivery device. 11.The medicament delivery device of claim 9, wherein the separatecomponent comprises an elongated plate-shaped member.
 12. The medicamentdelivery device of claim 11, wherein the housing is arranged withsupport elements preventing movement of the separate component whenassembled.
 13. The medicament delivery device of claim 12, wherein thesupport elements comprise a transversal stop element arranged to abut aproximal end of the separate component.
 14. The medicament deliverydevice of claim 13, wherein the transversal stop element is comprised inthe housing.
 15. The medicament delivery device of claim 13, wherein thesupport elements comprise longitudinally extending ledges arranged tosupport the separate component in all transversal directions.
 16. Themedicament delivery device of claim 13, wherein the support elementscomprise a transversal stop element arranged to abut a distal end of theseparate component.
 17. The medicament delivery device of claim 13,wherein the support elements are comprised in a component attachable tothe housing.
 18. The medicament delivery device of claim 9, wherein theseparate component comprises the ledge surfaces.
 19. The medicamentdelivery device of claim 5, wherein the locking element is positioned ata junction between the tubular part and the two arms of the medicamentdelivery member guard.
 20. The medicament delivery device of claim 5,wherein the locking element extends in a distal direction at an outwardinclination in relation to a longitudinal axis of the medicamentdelivery member guard.